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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INPP5D All Species: 26.36
Human Site: S814 Identified Species: 58
UniProt: Q92835 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92835 NP_001017915.1 1189 133292 S814 K S S D S D E S Y G E G C I A
Chimpanzee Pan troglodytes XP_526066 929 104074 I573 A T E T Q L P I Y T P L T H H
Rhesus Macaque Macaca mulatta XP_001114794 1258 138636 S833 K S M D G Y E S Y G E C V V A
Dog Lupus familis XP_542327 1264 138869 S839 K S M D G Y E S Y G E C V V A
Cat Felis silvestris
Mouse Mus musculus Q9ES52 1191 133524 S817 K S S D S D E S Y G E G C I A
Rat Rattus norvegicus P97573 1190 133575 S816 K S S D S D E S Y G E G C I A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520934 1019 113512 G663 P G G E K A Q G K P K P S T T
Chicken Gallus gallus XP_422567 1182 133482 S813 K S S D S D E S Y G E G C I A
Frog Xenopus laevis Q6P4S2 1019 115278 P663 T G I K Y N L P S W C D R I L
Zebra Danio Brachydanio rerio Q2I6J1 1266 140353 S817 K S L D G Y E S Y G E C V L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789838 1327 148052 S819 K S E D S D E S Y G E F V V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.8 41.3 40.9 N.A. 87.8 87.8 N.A. 38.7 68.2 56.5 43.1 N.A. N.A. N.A. N.A. 31
Protein Similarity: 100 77.8 57.5 56.8 N.A. 92.1 92 N.A. 48.5 78.7 67.1 57.9 N.A. N.A. N.A. N.A. 47.3
P-Site Identity: 100 6.6 60 60 N.A. 100 100 N.A. 0 100 6.6 60 N.A. N.A. N.A. N.A. 66.6
P-Site Similarity: 100 13.3 66.6 66.6 N.A. 100 100 N.A. 20 100 13.3 66.6 N.A. N.A. N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 64 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 28 37 0 0 % C
% Asp: 0 0 0 73 0 46 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 19 10 0 0 73 0 0 0 73 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 19 10 0 28 0 0 10 0 73 0 37 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % H
% Ile: 0 0 10 0 0 0 0 10 0 0 0 0 0 46 0 % I
% Lys: 73 0 0 10 10 0 0 0 10 0 10 0 0 0 0 % K
% Leu: 0 0 10 0 0 10 10 0 0 0 0 10 0 10 10 % L
% Met: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 0 0 0 0 10 10 0 10 10 10 0 0 0 % P
% Gln: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 0 73 37 0 46 0 0 73 10 0 0 0 10 0 10 % S
% Thr: 10 10 0 10 0 0 0 0 0 10 0 0 10 10 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 37 28 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 28 0 0 82 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _